Homebrew PCBs

Different methods work, I have used successfully: a heavy duty paper 
guillotine and a sheet metal shear. 

There are small relatively inexpensive shears available. 

The other recommended method is to use a water-cooled tile saw --- again 
relatively inexpensive, the water captures most of the dust.

I have also used a abrasive cutting disk on a dremel -- poor cut and 
very messy.  Table saw -- messy.  The dust is relatively toxic, so this 
is a poor method. 

David